Hangzhou Wencheng Chemical Biotech Co., Ltd.

99.5% p-Toluidine
99.5% p-Toluidine
99.5% p-Toluidine

99.5% p-Toluidine

Contact Us
  • Category

    o-Toluidine series

  • Describe

    p-Toluidine is an organic compound with the chemical formula C₇H₉N. It is one of the three positional isomers of methylaniline and belongs to the aromatic amine class of chemicals.

  • Cas No.

    106-49-0

  • Purity

    99.5%

  • Synonym(s)

    4-Methylaniline

Physical and chemical properties

  • 1. Chemical Identity
    • Chemical Name: p-Toluidine
    • IUPAC Name: 4-Methylaniline
    • Synonyms: 4-Aminotoluene, p-Aminotoluene, 1-Amino-4-methylbenzene
    • CAS Number: 106-49-0
    • EC Number: 203-403-1
    • Molecular Formula: C7H9N
    • Molecular Weight: 107.15 g/mol
  • 2. Physical Properties
    • Appearance: White to yellowish or brownish lustrous solid (leaflets or flakes). Darkens on exposure to air and light.
    • Odor: Faint, aromatic, aniline-like odor.
    • Melting Point: 43-45 °C (109-113 °F)
    • Boiling Point: 200 °C (392 °F) at 1013 hPa
    • Density: 1.046 g/cm³ at 20 °C
    • Solubility:
    • In Water: 7.5 g/L at 20 °C (Slightly soluble)
    • In Organic Solvents: Soluble in ethanol, diethyl ether, acetone, and carbon tetrachloride. Soluble in dilute acids.
    • Vapor Pressure: 0.15 hPa at 20 °C
    • Vapor Density: 3.9 (Air = 1)
  • 3. Chemical Properties and Stability
    • Stability: Stable under recommended storage conditions. Discolors on exposure to air and light.
    • Incompatibilities: Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides, and chloroformates. Reacts violently with nitric acid.
    • Hazardous Decomposition Products: Combustion may produce toxic fumes of carbon monoxide (CO), carbon dioxide (CO2), and nitrogen oxides (NOx).
  • 4. Other Key Data
    • Flash Point: 87 °C (189 °F) - Closed cup
    • Autoignition Temperature: 482 °C (900 °F)
    • Refractive Index (n44/D): 1.553
 

MSDS

99.5% p-Toluidine--MSDS     Download
 

Certificates Of Analysis

99.5% p-Toluidine--COA      Download
 

Application

1. Applied to pesticides, known pesticide intermediates and original drugs using p-toluidine as raw materials include benzofuron, etc.

2. Applied to dyes. The known dye intermediates and finished products using p-toluidine as raw material include dyes such as 4B acid, red base GL, methylamine red lake, basic fuchsin, methyl peri-acid and 4-aminotoluene-3-sulfonic acid, triphenylmethane dyes and oxazine dyes, etc.

3. Applied in medicine, the known pharmaceutical intermediate pyrimethamine uses p-toluidine as raw material

Safety Information

  • This information is a summary based on the Globally Harmonized System of Classification and Labelling of Chemicals (GHS).
  • 1. GHS Classification
    • Acute Toxicity, Oral (Category 3)
    • Acute Toxicity, Dermal (Category 3)
    • Acute Toxicity, Inhalation (Category 3)
    • Carcinogenicity (Category 1B)
    • Specific Target Organ Toxicity — Repeated Exposure (Category 2) (Affects blood)
    • Hazardous to the Aquatic Environment, Acute Hazard (Category 1)
    • Hazardous to the Aquatic Environment, Chronic Hazard (Category 1)
  • 2. GHS Label Elements
    • Pictograms:
      • Skull and Crossbones (GHS06)
      • Health Hazard (GHS08)
      • Environment (GHS09)
    • Signal Word: Danger
    • Hazard Statements (H-Statements):
      • H301 + H311 + H331: Toxic if swallowed, in contact with skin or if inhaled.
      • H350: May cause cancer.
      • H373: May cause damage to organs (blood) through prolonged or repeated exposure.
      • H410: Very toxic to aquatic life with long-lasting effects.
    • Precautionary Statements (P-Statements):
    • Prevention:
      • P201: Obtain special instructions before use.
      • P202: Do not handle until all safety precautions have been read and understood.
      • P273: Avoid release to the environment.
      • P280: Wear protective gloves, protective clothing, eye protection, and face protection.
    • Response:
      • P301 + P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
      • P302 + P352 + P312: IF ON SKIN: Wash with plenty of soap and water. Call a POISON CENTER or doctor/physician if you feel unwell.
      • P308 + P313: IF exposed or concerned: Get medical advice/attention.
    • P391: Collect spillage.
    • Storage:
      • P405: Store locked up.
    • Disposal:
      • P501: Dispose of contents/container to an approved hazardous waste disposal plant.
  • 3. Summary of Primary Hazards
    • Health Hazards: Toxic by all routes of exposure (ingestion, inhalation, and skin absorption). A primary hazard is the formation of methemoglobin, which reduces the oxygen-carrying capacity of the blood, leading to cyanosis (bluish skin), confusion, and headache. It is known to cause cancer.
    • Environmental Hazards: Very toxic to aquatic life with long-lasting effects. It is crucial to prevent its release into the environment.
    • Fire Hazards: Combustible solid. Dust can form explosive mixtures with air. When heated, it emits toxic fumes.

Follow Us
Get Updates

Contact Us